THE EFFECT OF CALCIUM TAINTED WATER ON CADMIUM INDUCED LIVER DAMAGE

ABSTRACT

Cadmium is recognize has a toxicant to both human and it’s environment and recent investigations have shown its level of toxicity in association in liver damage.  The aim of study is to determine the effect of calcium tainted water on cadmium induced liver damage  have been examine in this studies, 20 female wistar rat were used in this study the rats divided into four groups each containing 5 rats per group . The group one was maintained on normal feed and water only, the group 2 were exposed to cadmium only while the group three were exposed to calcium only and the group four were exposed simultaneously to cadmium and calcium. Each of the animal was given treatment based on their body weight (0.9 mg per kg body weight). The treatments were administered to the animals once a day for two weeks. At the end of two weeks the animals were sacrificed and the following biochemical markers were measured; Alkaline phosphatase, total protein, alanine amino transferase, total bilirubin and direct bilirubin.  All the biochemical markers were negatively affected by cadmium with exception to Albumin and total protein. The study reveal that cadmium has the potential to induce hepatotoxicity and calcium tainted water offer little ameliorating affect to cadmium induce liver damage.

 

  • Format:  Microsoft Word
  • Pages:  83
  • Price:  ₦3000
  • Chapters:  1-5
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